The Bifidobacterium longum NCIMB 702259T ctr gene codes for a novel cholate transporter.

نویسندگان

  • Claire E Price
  • Sharon J Reid
  • Arnold J M Driessen
  • Valerie R Abratt
چکیده

Preexposure of Bifidobacterium longum NCIMB 702259T to cholate caused increased resistance to cholate, chloramphenicol, and erythromycin. The B. longum ctr gene, encoding a cholate efflux transporter, was transformed into the efflux-negative mutant Escherichia coli KAM3, conferring resistance to bile salts and other antimicrobial compounds and causing the efflux of [14C]cholate.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 72 1  شماره 

صفحات  -

تاریخ انتشار 2006